Marc A. Busche, MD, PhD

I am currently a Programme Lead at the UK Dementia Research Institute at University College London. I performed my graduate studies in Germany in the laboratory of Arthur Konnerth, where I identified the pivotal role of early neural hyperactivity in the amyloid-plaque bearing Alzheimer brain. Then, I stayed at the Technical University of Munich to complete a residency in psychiatry and psychotherapy. While a resident, I conducted research as a tandem group leader at the Munich Cluster for Systems Neurology, focusing on the role of sleep-related long-range brain circuit dysfunction in Alzheimer’s disease (AD). As a recipient of the EMBO Long-Term Fellowship, I performed research with Bradley Hyman at MassGeneral Institute for Neurodegenerative Disease and Harvard Medical School, in which we identified that tau and amyloid work together to impair brain function in AD, and that tau predominates for certain aspects of that impairment. I am a board certified psychiatrist.