Dr. Hui Wang’s research interests include developing innovative optical techniques and combining them with MRI to study the structural-functional relationship of the brain. She has developed novel polarization-sensitive optical coherence tomography techniques for mapping the connectivity and associated neuronal architecture in ex-vivo human brains and investigating in-vivo neurovascular coupling in small animals at micrometer resolution. Using the techniques, She has been studying the circuitry and architecture disruptions with neurodegenerative diseases in the cerebrum and the cerebellum. By incorporating high-resolution microscopic images into MRI tools, the goal is to identify pathology-related alterations as potential diagnostic biomarkers and prospective therapeutic targets.
Massachusetts General Hospital
Boston, MA
Boston, MA