Dr. Hoang Le is a neuroscientist working on the roles of the innate immunity in Alzheimer’s disease (AD) in the Genetics and Aging Research Unit at the Massachusetts General Hospital and Harvard Medical School. Dr. Le received his BS in pharmacy from Hanoi University of Pharmacy in Vietnam in 2009. Dr. Le then moved to South Korea to pursue his doctoral research in the Department of Biochemistry, College of Pharmacy, Seoul National University (SNU), under the mentorship of Dr. Kyu-Won Kim. Dr. Le characterized the important roles of the adhesion molecule Ninjurin1 in a neuropsychiatric disease called obsessive-compulsive disorder (OCD) and in autoimmune neuroinflammation. After completing his Ph.D. program in pharmaceutical bioscience in 2017, Dr. Le joined the Unit of Dr. Rudolph E. Tanzi, a world-renowned geneticist, as a postdoctoral researcher. Dr. Le has learned cutting-edge AD research and had opportunities to work with eminent scientists researching AD pathogenesis and innate immunity, including his mentors Drs. Ana Griciuc and Rudolph E. Tanzi. His current research focuses on the microglial cells and TREM2. Specifically, Dr. Le is now investigating the roles of AD-linked mutations in TREM2, which is expressed in microglia, in the pathogenesis of AD. Dr. Le received the SNU Graduate Fellowship for Excellent Students and Daewoong Pharmaceutical Foundation Award for Excellent Students.
Massachusetts General Hospital