An Effective Tool for Understanding Dysfunctional Eye Drainage in Glaucoma

Project Summary

The most important risk factor in glaucoma is high pressure inside the eye from fluid that cannot properly drain away. Gaining a better understanding of this process is crucial for identifying new treatment targets in glaucoma. But lab models of the condition have several disadvantages that interfere with sorting out factors in fluid buildup.

To address this problem, Weiming Mao, PhD, and his team are developing a lab model that overcomes these disadvantages. The researchers expect their work to yield a novel tool that makes studying this drainage system in the eye much more straightforward. Such a tool will support scientists in better understanding how glaucoma develops and offer a way to test candidate treatments.