A Dietary Supplement in Treatment of Glaucoma

Project Goals

Mitochondria are the energy factories of cells. The mitochondria of RGCs lose function with age, probably due to age-related loss of nicotinamide adenine dinucleotide (NAD+), an enzyme cofactor needed for energy production, making the cells more susceptible to damage. The goal of this study is to test whether systemic delivery of the NAD+ precursor nicotinamide riboside, a dietary supplement, increases retinal NAD+ and protects RGCs in glaucoma models.

First published on: January 25, 2021

Last modified on: December 27, 2024