Understanding Early Molecular Events in Age-Related Macular Degeneration
Principal Investigator
Mentors
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Michael Dennis, PhD
Project Goals
The goal of this project is to improve understanding of specific molecular mechanisms that cause oxidative stress and inflammation in age-related macular degeneration.
Project Summary
Age-related macular degeneration (AMD) is a leading cause of vision loss among the elderly population. A significant challenge in addressing AMD is the lack of understanding of the early molecular events that contribute to its development. This project aims to explore a novel molecular switch that plays a role in the failed antioxidant and inflammatory responses in retinal pigment epithelium with aging. The findings are expected to identify new targets for therapeutics that are preventative or provide interventions early in the development of AMD.
Publications
First published on: August 02, 2024
Last modified on: September 10, 2024