Understanding Early Molecular Events in Age-Related Macular Degeneration

Project Summary

Age-related macular degeneration (AMD) is a leading cause of vision loss among the elderly population. A significant challenge in addressing AMD is the lack of understanding of the early molecular events that contribute to its development. This project aims to explore a novel molecular switch that plays a role in the failed antioxidant and inflammatory responses in retinal pigment epithelium with aging. The findings are expected to identify new targets for therapeutics that are preventative or provide interventions early in the development of AMD.