Treating Memory Loss in Alzheimer's Disease by Strengthening Synapses

Principal Investigator

Project Goals

People with Alzheimer's disease lose the ability to remember things, especially things they recently learned. We recently discovered that mice missing a specific molecule called Synaptotagmin3, have better memory than normal mice. We now want to test if removing this molecule from mice with Alzheimer's disease will improve their memory. If this works, it could be a way to treat humans with Alzheimer's disease to improve their memory.

Project Summary

People with Alzheimer's disease lose the ability to remember things, especially things they recently learned. We recently discovered that mice missing a specific molecule called Synaptotagmin3, have better memory than normal mice. We now want to test if removing this molecule from mice with Alzheimer's disease will improve their memory. If this works, it could be a way to treat humans with Alzheimer's disease to improve their memory.

First published on: November 12, 2019

Last modified on: April 29, 2024