Targeting Sleep Deficits to Restore Memory Function in Alzheimer's Disease
Detailed Non-Technical Summary
We use state-of-the-art technology such as optogenetics which allows us to control neuronal activity using light. In addition, we also use multiphoton microscopy to image the brain in action in living animals. Our study has two foreseeable benefits to the public. First, it will increase our understanding of the role of sleep in Alzheimer's disease and, therefore, will lead and direct future research efforts in the field. Second, our experiments can potentially lead to a discovery of a successful therapeutic for Alzheimer's disease.