Synthetic Peptides Transmitting Prion Disease to Mice

Project Summary

This project is a further development of Dr. Prusiner's previously begun study, Inducible Prion Diseases Caused by Artificial Mutations (see below). He is now attempting to transmit prion disease in mice using synthetically processed prions. Synthetic peptides are being used to help filter out variables in nature other than the prion that could cause prion disease. To complete this study, Dr. Prusiner received the BrightFocus Foundation's 25th Anniversary Research Award.