The Role of the Immune System in Driving Cognitive Decline
Principal Investigator
Mentors
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Katrin Andreasson, MD
Project Goals
To understand how the immune system worsens cognitive decline in aging and Alzheimer's disease.
Project Summary
During aging and Alzheimer's disease, certain inflammatory responses regulated by the immune system further exacerbate the disease and contribute to impaired cognition and memory. This study focuses on delineating the machinery necessary for immune cells to amplify damaging inflammation in the body and, ultimately, the brain. Using a novel method to target a specific immune cell mechanism, Dr. Ennerfelt and colleagues will assess how impeding its associated inflammatory pathways can curb cognitive decline and Alzheimer’s progression.
Publications
First published on: July 29, 2024
Last modified on: October 10, 2024