The Role of the Brain Vascular-Immune Processes in Alzheimer’s

Project Summary

Damage to the brain's blood vessels can triple the risk of developing Alzheimer's disease, and overactive immune cells may further exacerbate this damage. Here, researchers will study how these vascular-immune responses affect Alzheimer’s progression by analyzing brain scans and blood samples from 500+ individuals over time. Study outcomes will present a unique and more detailed picture of key and understudied mechanisms driving Alzheimer’s, thereby opening new perspectives on the development of personalized biomarkers and treatment strategies that target the interface between the vascular system, brain immune cells, and Alzheimer’s.