Dynamic O-Glycosylation and Alzheimer's Disease

Principal Investigator

Project Goals

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Publications

Kreppel LK, Hart GW. Regulation of a cytosolic and nuclear O-GlcNAc transferase. Role of the tetratricopeptide repeats. J Biol Chem. 1999 Nov 5;274(45):32015-22. PubMed  

Cole RN, Hart GW. Cytosolic O-glycosylation is abundant in nerve terminals. J Neurochem. 2001 Dec;79(5):1080-9. PubMed  

Cole RN, Hart GW. Glycosylation sites flank phosphorylation sites on synapsin I: O-linked N-acetylglucosamine residues are localized within domains mediating synapsin I interactions. J Neurochem. 1999 Jul;73(1):418-28. PubMed  

Hart GW, Cole RN, Kreppel, LK, Arnold CS, Comer FI, Iyer S, Cheng X, Carroll J, and Parker GJ. (1988) Glycosylation - A Major Challenge in Mass Spectrometry and Proteomics, in Proceedings of the 4th International Symposium on Mass Spectrometry in the Health &Life Sciences, eds. Burlingame, Carr, Baldwin. Human Press. Kreppel LK, Hart GW (1999). Functional Significance of O-GlcNAc Glycoproteins in the Cytoplasm and Nucleus, ed. Fukada, Hindsgaul. in Molecular and Cellular Glycobiology: Frontiers in Molecular Biology; Oxford Univ. Press. Oxford, UK. Acosta-Serrano A, Cole RN, Englund PT. Killing of Trypanosoma brucei by concanavalin A: structural basis of resistance in glycosylation mutants. J Mol Biol. 2000 Dec 8;304(4):633-44. PubMed  

Cole RN, Hart GW. Cytosolic O-glycosylation is abundant in nerve terminals. J Neurochem. 2001 Dec;79(5):1080-9. PubMed  

Cheng X, Cole RN, Zaia J, Hart GW. Alternative O-glycosylation/O-phosphorylation of the murine estrogen receptor beta. Biochemistry. 2000 Sep 26;39(38):11609-20. PubMed  

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First published on: June 11, 2008

Last modified on: November 24, 2024