Decoding Alzheimer’s Disease Genomes With Deep Learning

Project Summary

Dr. Naito’s research aims to unravel the genetic complexities of Alzheimer's disease. This project has two primary objectives: to develop a pipeline to predict the impact of genetic mutations on RNA processing in brain cells by state-of-the-art machine-learning technologies and to investigate how genetic mutations have an impact on individuals with Alzheimer’s via RNA processing by applying this pipeline to huge genomic data. A better understanding of genetic associations of Alzheimer’s will help in developing new treatments and identifying biomarkers.