BrightFocus Foundation
BrightFocus Foundation

Expanding and Enhancing LASI-DAD for Better Understanding of Alzheimer's Disease and Dementia

Principal Investigator

Project Goals

Our specific aims include:

  1. to perform high-quality venous blood-based assays of beta amyloid 42 and 40 (beta amyloid);
  2. to measure DNA methylation using stored DNA samples (methylation);
  3. to conduct a feasibility study of amyloid positron emission tomography (PET) scans across different geographic areas (PET scans); and
  4. to conduct a validation study, recruiting about 400 older adults from memory clinics, including those with Alzheimer’s disease, mild cognitive impairment, and cognitively normal.

Publications

First published on: April 12, 2024

Last modified on: November 24, 2024